BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50237102'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50237102
PNG
(CHEMBL4085352)
Show SMILES FC(F)(F)c1cccc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)c1
Show InChI InChI=1S/C22H15BrF3N5S/c23-14-4-2-6-16(10-14)29-20-18-11-17(7-8-19(18)27-12-28-20)31-21(32)30-15-5-1-3-13(9-15)22(24,25)26/h1-12H,(H,27,28,29)(H2,30,31,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 61n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged EGFR (668 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system

J Med Chem 60: 2853-2868 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01774
BindingDB Entry DOI: 10.7270/Q2K35WXP
More data for this
Ligand-Target Pair