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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50247550'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50247550
PNG
(4-(5-Bromoindole-3-yl)-6,7-dimethoxyquinazoline | ...)
Show SMILES COc1cc2ncnc(-c3c[nH]c4ccc(Br)cc34)c2cc1OC
Show InChI InChI=1S/C18H14BrN3O2/c1-23-16-6-12-15(7-17(16)24-2)21-9-22-18(12)13-8-20-14-4-3-10(19)5-11(13)14/h3-9,20H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 131n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of human EGFR tyrosine kinase activity


Eur J Med Chem 43: 1478-88 (2008)


Article DOI: 10.1016/j.ejmech.2007.09.018
BindingDB Entry DOI: 10.7270/Q2D50MRC
More data for this
Ligand-Target Pair