Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50274925'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50274925 (CHEMBL4126810) Show SMILES CN1CCN(CC1)c1ccc(Nc2cc3c(N[C@H]4CCCN(C)C4)nc(Nc4ccccc4)nc3cn2)nc1 |r| Show InChI InChI=1S/C29H36N10/c1-37-13-15-39(16-14-37)23-10-11-26(30-18-23)35-27-17-24-25(19-31-27)34-29(33-21-7-4-3-5-8-21)36-28(24)32-22-9-6-12-38(2)20-22/h3-5,7-8,10-11,17-19,22H,6,9,12-16,20H2,1-2H3,(H,30,31,35)(H2,32,33,34,36)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EGFR L858R mutant (unknown origin) using Poly(Glu,Tyr) as substrate after 40 mins by Kinase-Glo luminescence assay				Bioorg Med Chem 26: 3619-3633 (2018) Article DOI: 10.1016/j.bmc.2018.05.039 BindingDB Entry DOI: 10.7270/Q2Z3224Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50274925 (CHEMBL4126810) Show SMILES CN1CCN(CC1)c1ccc(Nc2cc3c(N[C@H]4CCCN(C)C4)nc(Nc4ccccc4)nc3cn2)nc1 |r| Show InChI InChI=1S/C29H36N10/c1-37-13-15-39(16-14-37)23-10-11-26(30-18-23)35-27-17-24-25(19-31-27)34-29(33-21-7-4-3-5-8-21)36-28(24)32-22-9-6-12-38(2)20-22/h3-5,7-8,10-11,17-19,22H,6,9,12-16,20H2,1-2H3,(H,30,31,35)(H2,32,33,34,36)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) using Poly(Glu,Tyr) as substrate after 40 mins by Kinase-Glo luminescence assay				Bioorg Med Chem 26: 3619-3633 (2018) Article DOI: 10.1016/j.bmc.2018.05.039 BindingDB Entry DOI: 10.7270/Q2Z3224Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50274925 (CHEMBL4126810) Show SMILES CN1CCN(CC1)c1ccc(Nc2cc3c(N[C@H]4CCCN(C)C4)nc(Nc4ccccc4)nc3cn2)nc1 |r| Show InChI InChI=1S/C29H36N10/c1-37-13-15-39(16-14-37)23-10-11-26(30-18-23)35-27-17-24-25(19-31-27)34-29(33-21-7-4-3-5-8-21)36-28(24)32-22-9-6-12-38(2)20-22/h3-5,7-8,10-11,17-19,22H,6,9,12-16,20H2,1-2H3,(H,30,31,35)(H2,32,33,34,36)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EGFR L858R/T790M double mutant (unknown origin) using Poly(Glu,Tyr) as substrate after 40 mins by Kinase-Glo luminescence assay				Bioorg Med Chem 26: 3619-3633 (2018) Article DOI: 10.1016/j.bmc.2018.05.039 BindingDB Entry DOI: 10.7270/Q2Z3224Q
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50274925 (CHEMBL4126810) Show SMILES CN1CCN(CC1)c1ccc(Nc2cc3c(N[C@H]4CCCN(C)C4)nc(Nc4ccccc4)nc3cn2)nc1 |r| Show InChI InChI=1S/C29H36N10/c1-37-13-15-39(16-14-37)23-10-11-26(30-18-23)35-27-17-24-25(19-31-27)34-29(33-21-7-4-3-5-8-21)36-28(24)32-22-9-6-12-38(2)20-22/h3-5,7-8,10-11,17-19,22H,6,9,12-16,20H2,1-2H3,(H,30,31,35)(H2,32,33,34,36)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	582	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using Poly(Glu,Tyr) as substrate after 40 mins by Kinase-Glo luminescence assay				Bioorg Med Chem 26: 3619-3633 (2018) Article DOI: 10.1016/j.bmc.2018.05.039 BindingDB Entry DOI: 10.7270/Q2Z3224Q
					More data for this Ligand-Target Pair