Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383046 (CHEMBL2031297) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD as substrate after 15 mins by time-resolved fluorimetric analysis | J Med Chem 55: 2251-64 (2012) Article DOI: 10.1021/jm201507x BindingDB Entry DOI: 10.7270/Q20K29M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383046 (CHEMBL2031297) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured at 1 hr by Western blot... | Bioorg Med Chem Lett 23: 5290-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.008 BindingDB Entry DOI: 10.7270/Q24Q7XX1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50383046 (CHEMBL2031297) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of wild type EGFR autophosphorylation in human A549 cells incubated for 1 hr followed by compound washout measured after 8 hrs by Western ... | Bioorg Med Chem Lett 23: 5290-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.008 BindingDB Entry DOI: 10.7270/Q24Q7XX1 | |||||||||||
More data for this Ligand-Target Pair |