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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50428416'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50428416
PNG
(CHEMBL2334002)
Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCNCCN
Show InChI InChI=1S/C19H21ClFN5O2/c1-27-17-10-16-13(9-18(17)28-7-6-23-5-4-22)19(25-11-24-16)26-12-2-3-15(21)14(20)8-12/h2-3,8-11,23H,4-7,22H2,1H3,(H,24,25,26)
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KEGG

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PC cid
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Similars
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of EGFR (unknown origin) using biotinylated-PTP1B (Tyr66) as substrate incubated for 5 mins prior to substrate addition measured after 1 h...

Eur J Med Chem 61: 84-94 (2013)


Article DOI: 10.1016/j.ejmech.2012.07.036
BindingDB Entry DOI: 10.7270/Q2X068CH
More data for this
Ligand-Target Pair