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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50457925'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50457925
PNG
(CHEMBL4207316)
Show SMILES CCc1c([nH]c2ccc(cc12)C(F)(F)F)C(=O)NC(CO)Cc1ccccc1
Show InChI InChI=1S/C21H21F3N2O2/c1-2-16-17-11-14(21(22,23)24)8-9-18(17)26-19(16)20(28)25-15(12-27)10-13-6-4-3-5-7-13/h3-9,11,15,26-27H,2,10,12H2,1H3,(H,25,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 900n/an/an/an/an/an/a



Aljouf University

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...

Eur J Med Chem 146: 260-273 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.042
BindingDB Entry DOI: 10.7270/Q25X2CKD
More data for this
Ligand-Target Pair