Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50458067'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50458067 (CHEMBL4215080) Show SMILES CN(C)C1CCN(CC1)c1ccc(Nc2cc3c(nc(Nc4ccc(F)cc4F)nc3cn2)N2CCOCC2)nc1 Show InChI InChI=1S/C29H33F2N9O/c1-38(2)20-7-9-39(10-8-20)21-4-6-26(32-17-21)36-27-16-22-25(18-33-27)35-29(34-24-5-3-19(30)15-23(24)31)37-28(22)40-11-13-41-14-12-40/h3-6,15-18,20H,7-14H2,1-2H3,(H,32,33,36)(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence assay				Eur J Med Chem 148: 221-237 (2018) Article DOI: 10.1016/j.ejmech.2018.02.051 BindingDB Entry DOI: 10.7270/Q2H70JF4
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50458067 (CHEMBL4215080) Show SMILES CN(C)C1CCN(CC1)c1ccc(Nc2cc3c(nc(Nc4ccc(F)cc4F)nc3cn2)N2CCOCC2)nc1 Show InChI InChI=1S/C29H33F2N9O/c1-38(2)20-7-9-39(10-8-20)21-4-6-26(32-17-21)36-27-16-22-25(18-33-27)35-29(34-24-5-3-19(30)15-23(24)31)37-28(22)40-11-13-41-14-12-40/h3-6,15-18,20H,7-14H2,1-2H3,(H,32,33,36)(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR L858R mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence assay				Eur J Med Chem 148: 221-237 (2018) Article DOI: 10.1016/j.ejmech.2018.02.051 BindingDB Entry DOI: 10.7270/Q2H70JF4
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50458067 (CHEMBL4215080) Show SMILES CN(C)C1CCN(CC1)c1ccc(Nc2cc3c(nc(Nc4ccc(F)cc4F)nc3cn2)N2CCOCC2)nc1 Show InChI InChI=1S/C29H33F2N9O/c1-38(2)20-7-9-39(10-8-20)21-4-6-26(32-17-21)36-27-16-22-25(18-33-27)35-29(34-24-5-3-19(30)15-23(24)31)37-28(22)40-11-13-41-14-12-40/h3-6,15-18,20H,7-14H2,1-2H3,(H,32,33,36)(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR L858R/T790M double mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence a...				Eur J Med Chem 148: 221-237 (2018) Article DOI: 10.1016/j.ejmech.2018.02.051 BindingDB Entry DOI: 10.7270/Q2H70JF4
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50458067 (CHEMBL4215080) Show SMILES CN(C)C1CCN(CC1)c1ccc(Nc2cc3c(nc(Nc4ccc(F)cc4F)nc3cn2)N2CCOCC2)nc1 Show InChI InChI=1S/C29H33F2N9O/c1-38(2)20-7-9-39(10-8-20)21-4-6-26(32-17-21)36-27-16-22-25(18-33-27)35-29(34-24-5-3-19(30)15-23(24)31)37-28(22)40-11-13-41-14-12-40/h3-6,15-18,20H,7-14H2,1-2H3,(H,32,33,36)(H,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR L858R/T790M/C797S mutant (unknown origin) using Poly (Glu, Tyr) as substrate after 40 mins by kinase-Glo luminescence as...				Eur J Med Chem 148: 221-237 (2018) Article DOI: 10.1016/j.ejmech.2018.02.051 BindingDB Entry DOI: 10.7270/Q2H70JF4
					More data for this Ligand-Target Pair