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Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50464779'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50464779
PNG
(CHEMBL4293326)
Show SMILES Cc1oc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1C(O)=O
Show InChI InChI=1S/C21H15ClFN3O4/c1-11-17(21(27)28)18-19(24-10-25-20(18)30-11)26-14-5-6-16(15(22)8-14)29-9-12-3-2-4-13(23)7-12/h2-8,10H,9H2,1H3,(H,27,28)(H,24,25,26)
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 951n/an/an/an/an/an/a



Ain Shams University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal His/N-terminal GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells using bi...

Eur J Med Chem 144: 330-348 (2018)


Article DOI: 10.1016/j.ejmech.2017.12.022
BindingDB Entry DOI: 10.7270/Q27D2XS5
More data for this
Ligand-Target Pair