Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50582238 (CHEMBL5076986) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) measured by ELISA | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00555 BindingDB Entry DOI: 10.7270/Q2CC14KG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50582238 (CHEMBL5076986) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of wild type EGFR (unknown origin) measured by ELISA | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00555 BindingDB Entry DOI: 10.7270/Q2CC14KG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |