Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [671-1210,L858R] (Homo sapiens (Human)) | BDBM27962 (1-((1r,4r)-4-morpholinocyclohexyl)-3-(2-(thiophen-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 361 | n/a | n/a | n/a | n/a | 7.5 | 23 |
Abbott Laboratories | Assay Description Assays were performed in 96-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of ... | Bioorg Med Chem Lett 19: 1718-21 (2009) Article DOI: 10.1016/j.bmcl.2009.01.086 BindingDB Entry DOI: 10.7270/Q2CJ8BTG | |||||||||||
More data for this Ligand-Target Pair |