Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [695-1022]' and Ligand = 'BDBM525485'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [695-1022] (Homo sapiens (Human))	BDBM525485 (US11174245, # I-135) Show SMILES Cn1cc(cn1)-c1cc(cc(F)n1)C(=O)\N=c1/[nH]c2cc(CN3CCOCC3)ccc2n1[C@@H]1CC[C@H](O)CC1 |r,wU:32.36,35.40,(7.08,-4.73,;7.08,-3.19,;5.83,-2.28,;6.31,-.82,;7.85,-.82,;8.33,-2.28,;5.54,.52,;4,.52,;3.23,1.85,;4,3.19,;5.54,3.19,;6.31,4.52,;6.31,1.85,;1.69,1.85,;.92,3.19,;.92,.52,;-.62,.52,;-1.53,1.76,;-2.99,1.29,;-4.32,2.06,;-5.66,1.29,;-6.99,2.06,;-6.99,3.6,;-5.66,4.37,;-5.66,5.91,;-6.99,6.68,;-8.33,5.91,;-8.33,4.37,;-5.66,-.25,;-4.32,-1.02,;-2.99,-.25,;-1.53,-.73,;-1.13,-2.22,;-2.22,-3.3,;-1.82,-4.79,;-.33,-5.19,;.07,-6.68,;.76,-4.1,;.36,-2.61,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 5 μL of EGFR enzyme form in assay buffer (50 mM HEPES pH 7.3, 10 mM MgCl2, 1 mM EGTA, 0.01% Tween 20, 2 mM DTT) are dispensed into columns 1-23,...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP56F9
					More data for this Ligand-Target Pair