Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [L858R]' and Ligand = 'BDBM270540'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [L858R] (Homo sapiens (Human))	BDBM270540 (N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...) Show SMILES COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1 Show InChI InChI=1S/C24H23ClN6O4/c1-5-20(32)27-14-10-11-19(35-4)18(12-14)29-24-26-13-16(25)22(30-24)28-17-9-7-6-8-15(17)21(33)23(34)31(2)3/h5-13H,1H2,2-4H3,(H,27,32)(H2,26,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
BETTA PHARMACEUTICALS CO., LTD. US Patent					Assay Description Kinase Assay Protocol:Bar-coded Corning, low volume NBS, black 384-well plate (Corning Cat. #4514)1. 2.5 μL—4× Test Compound or 100 nL 100×...				US Patent US9783524 (2017) BindingDB Entry DOI: 10.7270/Q2WS8WCB
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [L858R] (Homo sapiens (Human))	BDBM270540 (N-(3-(5-chloro-4-(2-(2- (dimethylamino)-2-oxoacety...) Show SMILES COc1ccc(NC(=O)C=C)cc1Nc1ncc(Cl)c(Nc2ccccc2C(=O)C(=O)N(C)C)n1 Show InChI InChI=1S/C24H23ClN6O4/c1-5-20(32)27-14-10-11-19(35-4)18(12-14)29-24-26-13-16(25)22(30-24)28-17-9-7-6-8-15(17)21(33)23(34)31(2)3/h5-13H,1H2,2-4H3,(H,27,32)(H2,26,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
BETTA PHARMACEUTICALS CO., LTD. US Patent					Assay Description TBD				US Patent US10059688 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NDZ
					More data for this Ligand-Target Pair