Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [T790M,L858R]' and Ligand = 'BDBM149403'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human))	BDBM149403 (US10434101, Compound I-3 | US11096942, Compound I-...) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO Show InChI InChI=1S/C26H27ClN6O5/c1-3-23(35)29-17-5-4-6-19(13-17)38-25-20(27)15-28-26(31-25)30-21-8-7-18(14-22(21)37-2)32-9-11-33(12-10-32)24(36)16-34/h3-8,13-15,34H,1,9-12,16H2,2H3,(H,29,35)(H,28,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...				Citation and Details BindingDB Entry DOI: 10.7270/Q2GT5RBQ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor [T790M,L858R] (Homo sapiens (Human))	BDBM149403 (US10434101, Compound I-3 | US11096942, Compound I-...) Show SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)CO Show InChI InChI=1S/C26H27ClN6O5/c1-3-23(35)29-17-5-4-6-19(13-17)38-25-20(27)15-28-26(31-25)30-21-8-7-18(14-22(21)37-2)32-9-11-33(12-10-32)24(36)16-34/h3-8,13-15,34H,1,9-12,16H2,2H3,(H,29,35)(H,28,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Celgene CAR LLC US Patent					Assay Description Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS001A) and ap...				US Patent US10434101 (2019) BindingDB Entry DOI: 10.7270/Q2NK3HD3
					More data for this Ligand-Target Pair