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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50523048'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM50523048
PNG
(CHEMBL4462970)
Show SMILES CC1=C([C@@H](Oc2cc(F)c(O)cc12)c1ccc(OCCN2CC(CF)C2)cc1)c1ccc(F)cc1 |r,t:1|
Show InChI InChI=1S/C28H26F3NO3/c1-17-23-12-25(33)24(31)13-26(23)35-28(27(17)19-2-6-21(30)7-3-19)20-4-8-22(9-5-20)34-11-10-32-15-18(14-29)16-32/h2-9,12-13,18,28,33H,10-11,14-16H2,1H3/t28-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.580n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by FITC/Hoechst 33342 staining based immunofluorescence imaging analysis

Bioorg Med Chem Lett 29: 2090-2093 (2019)


Article DOI: 10.1016/j.bmcl.2019.07.013
BindingDB Entry DOI: 10.7270/Q2ZK5M3V
More data for this
Ligand-Target Pair