Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Estrogen receptor [298-554,Y537S]' and Ligand = 'BDBM521267'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor [298-554,Y537S] (Homo sapiens (Human))	BDBM521267 (5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...) Show SMILES Oc1cccc(c1)C1=C(c2ccc(N[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2OCC1 |r,c:8| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonistic potency of compounds was evaluated using LanthaScreen® TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8BT3
					More data for this Ligand-Target Pair