Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Estrogen receptor [307-554]' and Ligand = 'BDBM300996'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor [307-554] (Homo sapiens (Human))	BDBM300996 (2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(6- fluoro-5-...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)CO)c1ccc(NC2CN(CCCF)C2)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The assay was performed as follows with all reagent additions carried out using the Beckman Coulter BioRAPTR FRD microfluidic workstation:1. Acoustic...				US Patent US10961241 (2021) BindingDB Entry DOI: 10.7270/Q2BR8W8P
					More data for this Ligand-Target Pair
Estrogen receptor [307-554] (Homo sapiens (Human))	BDBM300996 (2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(6- fluoro-5-...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC(F)(F)CO)c1ccc(NC2CN(CCCF)C2)c(F)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description ER: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assay...				US Patent US10590130 (2020) BindingDB Entry DOI: 10.7270/Q28S4SX5
					More data for this Ligand-Target Pair