Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Estrogen receptor [Y537S]' and Ligand = 'BDBM263757'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM263757 (5-[4-[(3S)- 1-(3- fluoropropyl)- pyrrolidin-3- yl]...) Show SMILES COc1cc(C)c(cn1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2CCC1 |r,c:10| Show InChI InChI=1S/C31H35FN2O3/c1-21-17-30(36-2)33-19-29(21)28-6-3-5-23-18-24(35)9-12-27(23)31(28)22-7-10-25(11-8-22)37-26-13-16-34(20-26)15-4-14-32/h7-12,17-19,26,35H,3-6,13-16,20H2,1-2H3/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.4	25
SANOFI US Patent					Assay Description It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...				US Patent US9714221 (2017) BindingDB Entry DOI: 10.7270/Q2N58PB1
					More data for this Ligand-Target Pair