BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Estrogen receptor [Y537S]' and Ligand = 'BDBM443441'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443441 (US10654866, Example 8 \| US11117902, Example 8 \| US...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443441 (US10654866, Example 8 \| US11117902, Example 8 \| US...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
TBA					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443441 (US10654866, Example 8 \| US11117902, Example 8 \| US...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
TBA					More data for this Ligand-Target Pair