Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50397432'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50397432 (CHEMBL2170560) Show SMILES CO[C@@H]1OC[C@@H](O[C@H]1Oc1cc2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)c2c(OC)c1)C(=O)N(C)C)c1ccccc1)c1ccc(OC)cc1)[C@@H](O)CO |r| Show InChI InChI=1S/C35H41NO12/c1-36(2)31(40)27-28(19-9-7-6-8-10-19)35(20-11-13-21(42-3)14-12-20)34(41,30(27)39)29-24(43-4)15-22(16-25(29)48-35)46-33-32(44-5)45-18-26(47-33)23(38)17-37/h6-16,23,26-28,30,32-33,37-39,41H,17-18H2,1-5H3/t23-,26+,27+,28+,30+,32+,33+,34-,35-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Infinity Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of eIF4FA in human MDA-MB-231 cells transfected with c-myc- 5'-UTR-luciferase construct assessed as reduction in translation initiation in...				J Med Chem 55: 8859-78 (2012) Article DOI: 10.1021/jm3011542 BindingDB Entry DOI: 10.7270/Q23R0V1X
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50397432 (CHEMBL2170560) Show SMILES CO[C@@H]1OC[C@@H](O[C@H]1Oc1cc2O[C@]3([C@@H]([C@H]([C@@H](O)[C@@]3(O)c2c(OC)c1)C(=O)N(C)C)c1ccccc1)c1ccc(OC)cc1)[C@@H](O)CO |r| Show InChI InChI=1S/C35H41NO12/c1-36(2)31(40)27-28(19-9-7-6-8-10-19)35(20-11-13-21(42-3)14-12-20)34(41,30(27)39)29-24(43-4)15-22(16-25(29)48-35)46-33-32(44-5)45-18-26(47-33)23(38)17-37/h6-16,23,26-28,30,32-33,37-39,41H,17-18H2,1-5H3/t23-,26+,27+,28+,30+,32+,33+,34-,35-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Infinity Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of eIF4FA in human MDA-MB-231 cells transfected with tubulin 5'-UTR-luciferase construct assessed as reduction in translation initiation i...				J Med Chem 55: 8859-78 (2012) Article DOI: 10.1021/jm3011542 BindingDB Entry DOI: 10.7270/Q23R0V1X
					More data for this Ligand-Target Pair