Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50482562'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50482562 (CHEMBL1222309 | Hippuristanol 3,11-Diacetate) Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC[C@@]5([H])C[C@@H](CC[C@]5(C)[C@@]4([H])[C@H](C[C@]3(C)[C@@]1([H])[C@@](C)(O)[C@]1(C[C@H](C)C(C)(C)O1)O2)OC(C)=O)OC(C)=O |r| Show InChI InChI=1S/C32H50O7/c1-17-15-32(39-28(17,4)5)31(8,35)27-24(38-32)14-23-22-10-9-20-13-21(36-18(2)33)11-12-29(20,6)26(22)25(37-19(3)34)16-30(23,27)7/h17,20-27,35H,9-16H2,1-8H3/t17-,20-,21+,22-,23-,24-,25-,26+,27-,29-,30-,31+,32+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of eIF4A-mediated cap-dependent protein synthesis in FF-HCV-Ren mRNA transfected Swiss mouse Krebs2 cell extract by [35S]methionine metabo...				Nat Chem Biol 2: 213-20 (2006) Article DOI: 10.1038/nchembio776 BindingDB Entry DOI: 10.7270/Q2F47RZB
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