Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 2-alpha kinase 3 [540-1115]' and Ligand = 'BDBM482161'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 3 [540-1115] (Homo sapiens (Human))	BDBM482161 (N-[3-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-...) Show SMILES COc1ccc(cc1Cl)S(=O)(=O)Nc1cccc(-c2cn(C)c3ncnc(N)c23)c1F Show InChI InChI=1S/C20H17ClFN5O3S/c1-27-9-13(17-19(23)24-10-25-20(17)27)12-4-3-5-15(18(12)22)26-31(28,29)11-6-7-16(30-2)14(21)8-11/h3-10,26H,1-2H3,(H2,23,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The biochemical activity of compounds was determined by incubation with PERK recombinant enzyme (cytoplasmic domain corresponding to residues 540-111...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C2518M
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 2-alpha kinase 3 [540-1115] (Homo sapiens (Human))	BDBM482161 (N-[3-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-...) Show SMILES COc1ccc(cc1Cl)S(=O)(=O)Nc1cccc(-c2cn(C)c3ncnc(N)c23)c1F Show InChI InChI=1S/C20H17ClFN5O3S/c1-27-9-13(17-19(23)24-10-25-20(17)27)12-4-3-5-15(18(12)22)26-31(28,29)11-6-7-16(30-2)14(21)8-11/h3-10,26H,1-2H3,(H2,23,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The biochemical activity of compounds was determined by incubation with PERK recombinant enzyme (cytoplasmic domain corresponding to residues 540-111...				Citation and Details BindingDB Entry DOI: 10.7270/Q2C2518M
					More data for this Ligand-Target Pair