Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM167382'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM167382 (US9073881, 134) Show SMILES OC(=O)c1cc(ccc1-c1ccc(F)cc1Cl)-c1nc(cs1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H11Cl3FNO2S/c23-17-6-2-11(8-19(17)25)20-10-30-21(27-20)12-1-4-14(16(7-12)22(28)29)15-5-3-13(26)9-18(15)24/h1-10H,(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.0	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description Human eIF4E (aa 28-217) with a C-terminal His tag (HH-eIF4E) was expressed in E. coli in inclusion bodies. The protein was solubilized with 8 M urea ...				US Patent US9073881 (2015) BindingDB Entry DOI: 10.7270/Q2513X0T
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