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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM50386772'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Eukaryotic translation initiation factor 4E


(Homo sapiens (Human))		BDBM50386772
PNG
(CHEMBL2046913)
Show SMILES Nc1nc2c(cn(CCOc3ccc(Cl)cc3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C19H22ClN4O9P/c20-9-1-3-10(4-2-9)31-6-5-24-7-11(13-14(24)18(27)23-19(21)22-13)17-16(26)15(25)12(33-17)8-32-34(28,29)30/h1-4,7,12,15-17,25-26H,5-6,8H2,(H2,28,29,30)(H3,21,22,23,27)/t12-,15-,16-,17+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.58E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Competitive inhibition of [3H]m7-GTP binding to human FLAG-His6 tagged eIF4E expressed in Escherichia coli by scintillation proximity assay

J Med Chem 55: 3837-51 (2012)


Article DOI: 10.1021/jm300037x
BindingDB Entry DOI: 10.7270/Q27082GX
More data for this
Ligand-Target Pair