Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E' and Ligand = 'BDBM50386778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50386778 (CHEMBL2046919) Show SMILES CCOP(=O)(OCC)c1ccc(cc1)-c1nc2nc(NC)[nH]c(=O)c2n1CCOc1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN5O5P/c1-4-34-36(32,35-5-2)19-12-6-16(7-13-19)22-27-21-20(23(31)29-24(26-3)28-21)30(22)14-15-33-18-10-8-17(25)9-11-18/h6-13H,4-5,14-15H2,1-3H3,(H2,26,28,29,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Competitive inhibition of [3H]m7-GTP binding to human FLAG-His6 tagged eIF4E expressed in Escherichia coli by scintillation proximity assay				J Med Chem 55: 3837-51 (2012) Article DOI: 10.1021/jm300037x BindingDB Entry DOI: 10.7270/Q27082GX
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