Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50325500'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325500 (2-(4-isopropylphenyl)-4,7-dimethoxy-1-(2-methoxyet...) Show SMILES COCCn1c(nc2c(OC)ccc(OC)c12)-c1ccc(cc1)C(C)C Show InChI InChI=1S/C21H26N2O3/c1-14(2)15-6-8-16(9-7-15)21-22-19-17(25-4)10-11-18(26-5)20(19)23(21)12-13-24-3/h6-11,14H,12-13H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
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