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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50325502'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50325502
PNG
(4,7-dibromo-2-(4-isopropylphenyl)-1-(2-methoxyethy...)
Show SMILES COCCn1c(nc2c(Br)ccc(Br)c12)-c1ccc(cc1)C(C)C
Show InChI InChI=1S/C19H20Br2N2O/c1-12(2)13-4-6-14(7-5-13)19-22-17-15(20)8-9-16(21)18(17)23(19)10-11-24-3/h4-9,12H,10-11H2,1-3H3
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n/an/a 1.00E+3n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization

Bioorg Med Chem Lett 20: 5161-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.016
BindingDB Entry DOI: 10.7270/Q2H70G1X
More data for this
Ligand-Target Pair