Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50325517'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50325517 (4-bromo-5-(3,4-dimethoxybenzyl)-2-(4-isopropylphen...) Show SMILES COCCn1c(nc2c(Br)c(Cc3ccc(OC)c(OC)c3)cc(OC)c12)-c1ccc(cc1)C(C)C Show InChI InChI=1S/C29H33BrN2O4/c1-18(2)20-8-10-21(11-9-20)29-31-27-26(30)22(15-19-7-12-23(34-4)24(16-19)35-5)17-25(36-6)28(27)32(29)13-14-33-3/h7-12,16-18H,13-15H2,1-6H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Antagonist activity at human CaSR expressed in hamster fibroblasts assessed as inhibition of calcium mobilization				Bioorg Med Chem Lett 20: 5161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.016 BindingDB Entry DOI: 10.7270/Q2H70G1X
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