Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eyes absent homolog 2 [253-538]' and Ligand = 'BDBM231627'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eyes absent homolog 2 [253-538] (Homo sapiens (Human))	BDBM231627 (MLS000585814) Show SMILES Cc1ccccc1C(=O)N\N=C\c1ccc(Sc2ccccn2)o1 Show InChI InChI=1S/C18H15N3O2S/c1-13-6-2-3-7-15(13)18(22)21-20-12-14-9-10-17(23-14)24-16-8-4-5-11-19-16/h2-12H,1H3,(H,21,22)/b20-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	6.5	25
University of Colorado School of Medicine					Assay Description Eya activity was measured in 50-μl reactions using black, 96-well, half-volume microtiter plates (Greiner Bio-one) with the substrate OMFP (3-O-...				J Biol Chem 289: 16349-61 (2014) Article DOI: 10.1074/jbc.M114.566729 BindingDB Entry DOI: 10.7270/Q2CC0ZJK
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