Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM137291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137291 (US8871790, 375) Show SMILES CC(C)CNC(=O)Nc1cc(ccc1C)-c1nnc2CC(CCn12)c1ccc(cc1)C#N Show InChI InChI=1S/C25H28N6O/c1-16(2)15-27-25(32)28-22-12-21(7-4-17(22)3)24-30-29-23-13-20(10-11-31(23)24)19-8-5-18(14-26)6-9-19/h4-9,12,16,20H,10-11,13,15H2,1-3H3,(H2,27,28,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
					More data for this Ligand-Target Pair