Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM137306'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137306 (US8871790, 392) Show SMILES Cc1cc(C2CCC2)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2CCOCc2[nH]1 Show InChI InChI=1S/C30H32N4O2/c1-19-15-25(23-3-2-4-23)26(29-32-27-11-14-36-18-28(27)33-29)16-24(19)30(35)34-12-9-22(10-13-34)21-7-5-20(17-31)6-8-21/h5-8,15-16,22-23H,2-4,9-14,18H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
					More data for this Ligand-Target Pair