Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM137328'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM137328 (US8871790, 414) Show SMILES FC1(CCN(CC1)C(=O)c1ccc(C2CCC2)c(c1)-c1nc2CCOCc2[nH]1)c1ccc(cc1)C#N Show InChI InChI=1S/C29H29FN4O2/c30-29(22-7-4-19(17-31)5-8-22)11-13-34(14-12-29)28(35)21-6-9-23(20-2-1-3-20)24(16-21)27-32-25-10-15-36-18-26(25)33-27/h4-9,16,20H,1-3,10-15,18H2,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. US Patent					Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...				US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3
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