Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid synthase (Homo sapiens (Human)) | BDBM50426446 (CHEMBL2322371) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
3-V Biosciences, Inc. US Patent | Assay Description The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS... | US Patent US8871790 (2014) BindingDB Entry DOI: 10.7270/Q2PG1QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid synthase (Homo sapiens (Human)) | BDBM50426446 (CHEMBL2322371) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
3-V Biosciences, Inc. Curated by ChEMBL | Assay Description Inhibition of human FASN assessed as release of co-enzyme A | ACS Med Chem Lett 4: 113-7 (2013) Article DOI: 10.1021/ml300335r BindingDB Entry DOI: 10.7270/Q2P84D76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid synthase (Rattus norvegicus) | BDBM50426446 (CHEMBL2322371) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
3-V Biosciences, Inc. Curated by ChEMBL | Assay Description Inhibition of rat FASN assessed as release of co-enzyme A | ACS Med Chem Lett 4: 113-7 (2013) Article DOI: 10.1021/ml300335r BindingDB Entry DOI: 10.7270/Q2P84D76 | |||||||||||
More data for this Ligand-Target Pair |