Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM143291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM143291 (US9682953, 2.E-27) Show SMILES Cc1nc(Oc2cccc(C=C3CCC(CC3)NC(=O)c3cnc(N)nc3)c2)ccc1Cl |(-11.06,-6.22,;-9.72,-5.45,;-8.39,-6.22,;-7.06,-5.45,;-5.72,-6.22,;-4.39,-5.45,;-4.39,-3.91,;-3.06,-3.14,;-1.72,-3.91,;-1.72,-5.45,;-.39,-6.22,;.94,-5.45,;2.28,-6.22,;3.61,-5.45,;3.61,-3.91,;2.28,-3.14,;.94,-3.91,;4.95,-3.14,;6.28,-3.91,;6.28,-5.45,;7.61,-3.14,;8.95,-3.91,;10.28,-3.14,;10.28,-1.6,;11.61,-.83,;8.95,-.83,;7.61,-1.6,;-3.06,-6.22,;-7.06,-3.91,;-8.39,-3.14,;-9.72,-3.91,;-11.06,-3.14,)| Show InChI InChI=1S/C24H24ClN5O2/c1-15-21(25)9-10-22(29-15)32-20-4-2-3-17(12-20)11-16-5-7-19(8-6-16)30-23(31)18-13-27-24(26)28-14-18/h2-4,9-14,19H,5-8H2,1H3,(H,30,31)(H2,26,27,28)/b16-11-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	25
ADVINUS THERAPEUTICS LIMITED US Patent					Assay Description All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...				US Patent US9682953 (2017) BindingDB Entry DOI: 10.7270/Q2BR8QBH
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