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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM50342072'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50342072
PNG
((S)-methyl 6-(2-(6-(benzyloxy)-1,2,3,4-tetrahydron...)
Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)[C@H]1CCc2cc(OCc3ccccc3)ccc2C1 |r|
Show InChI InChI=1S/C28H24N2O5/c1-33-28(32)24-9-5-8-23(30-24)25-16-29-27(35-25)26(31)21-11-10-20-15-22(13-12-19(20)14-21)34-17-18-6-3-2-4-7-18/h2-9,12-13,15-16,21H,10-11,14,17H2,1H3/t21-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
18n/an/an/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion


J Med Chem 54: 2805-22 (2011)


Article DOI: 10.1021/jm101597x
BindingDB Entry DOI: 10.7270/Q2ZK5H08
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50342072
PNG
((S)-methyl 6-(2-(6-(benzyloxy)-1,2,3,4-tetrahydron...)
Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)[C@H]1CCc2cc(OCc3ccccc3)ccc2C1 |r|
Show InChI InChI=1S/C28H24N2O5/c1-33-28(32)24-9-5-8-23(30-24)25-16-29-27(35-25)26(31)21-11-10-20-15-22(13-12-19(20)14-21)34-17-18-6-3-2-4-7-18/h2-9,12-13,15-16,21H,10-11,14,17H2,1H3/t21-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion


J Med Chem 54: 2805-22 (2011)


Article DOI: 10.1021/jm101597x
BindingDB Entry DOI: 10.7270/Q2ZK5H08
More data for this
Ligand-Target Pair