Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1 [30-579]' and Ligand = 'BDBM155358'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM155358 (US10383871, Example 4 | US10918640, Example 4 | US...) Show SMILES O=C(Nc1cccnc1)N1CC(C1)Oc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H19N3O2/c25-21(23-18-7-4-12-22-13-18)24-14-20(15-24)26-19-10-8-17(9-11-19)16-5-2-1-3-6-16/h1-13,20H,14-15H2,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	8.2	25
Vernalis (R&D) Ltd. US Patent					Assay Description FAAH activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolysis of th...				US Patent US9006269 (2015) BindingDB Entry DOI: 10.7270/Q2DB80KF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM155358 (US10383871, Example 4 | US10918640, Example 4 | US...) Show SMILES O=C(Nc1cccnc1)N1CC(C1)Oc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H19N3O2/c25-21(23-18-7-4-12-22-13-18)24-14-20(15-24)26-19-10-8-17(9-11-19)16-5-2-1-3-6-16/h1-13,20H,14-15H2,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Active rat FAAH protein (30-579) was isolated as described in the literature. The coding sequence of amino adds 30-579 of rat FAAH were cloned into t...				US Patent US10918640 (2021) BindingDB Entry DOI: 10.7270/Q28G8PT0
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM155358 (US10383871, Example 4 | US10918640, Example 4 | US...) Show SMILES O=C(Nc1cccnc1)N1CC(C1)Oc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H19N3O2/c25-21(23-18-7-4-12-22-13-18)24-14-20(15-24)26-19-10-8-17(9-11-19)16-5-2-1-3-6-16/h1-13,20H,14-15H2,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd. US Patent					Assay Description Active rat FAAH protein (30-579) was isolated as described in the literature. The coding sequence of amino acids 30-579 of rat FAAH were cloned into ...				US Patent US10383871 (2019) BindingDB Entry DOI: 10.7270/Q2NV9MNH
					More data for this Ligand-Target Pair