Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Time-dependent inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide preincubated for 6 hrs by Dix... | J Med Chem 57: 1079-89 (2014) Article DOI: 10.1021/jm401820q BindingDB Entry DOI: 10.7270/Q2HX1F5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Time-dependent inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide preincubated for 3 hrs by Dix... | J Med Chem 57: 1079-89 (2014) Article DOI: 10.1021/jm401820q BindingDB Entry DOI: 10.7270/Q2HX1F5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Time-dependent inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide preincubated for 1 hr by Dixo... | J Med Chem 57: 1079-89 (2014) Article DOI: 10.1021/jm401820q BindingDB Entry DOI: 10.7270/Q2HX1F5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Inhibition of rat FAAH preincubated for 20 mins | Bioorg Med Chem Lett 18: 4838-43 (2008) Article DOI: 10.1016/j.bmcl.2008.07.081 BindingDB Entry DOI: 10.7270/Q23T9H2B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli | J Med Chem 53: 230-40 (2010) Article DOI: 10.1021/jm9012196 BindingDB Entry DOI: 10.7270/Q2FN168N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Max-Planck Institute of Molecular Physiology Curated by ChEMBL | Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli | Bioorg Med Chem 20: 1100-12 (2012) Article DOI: 10.1016/j.bmc.2011.11.027 BindingDB Entry DOI: 10.7270/Q2G16191 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli | J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli using [14C]oleamide as substrate assessed as oleic acid formation by Dixon plot anal... | Bioorg Med Chem 22: 2763-70 (2014) Article DOI: 10.1016/j.bmc.2014.03.013 BindingDB Entry DOI: 10.7270/Q2X92CVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Binding affinity against purified rat Fatty-acid amide hydrolase (FAAH) expressed in Escherichia coli | Bioorg Med Chem Lett 15: 103-6 (2004) Article DOI: 10.1016/j.bmcl.2004.10.025 BindingDB Entry DOI: 10.7270/Q2MC8ZGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 | J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology Curated by ChEMBL | Assay Description Inhibition of rat FAAH expressed in Escherichia coli | J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat FAAH | Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli | J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd Curated by ChEMBL | Assay Description Inhibition of rat FAAH incubated 1 hr prior to addition of arachidonylaminomethylcoumarin amide | Bioorg Med Chem Lett 19: 4241-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.097 BindingDB Entry DOI: 10.7270/Q28S4PZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 306 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd Curated by ChEMBL | Assay Description Inhibition of rat FAAH incubated 3 hrs prior to addition of arachidonylaminomethylcoumarin amide | Bioorg Med Chem Lett 19: 4241-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.097 BindingDB Entry DOI: 10.7270/Q28S4PZC | |||||||||||
More data for this Ligand-Target Pair |