Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1 [30-579]' and Ligand = 'BDBM50307805'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50307805 (4-Acetamidophenyl 2-(2-(trifluoromethyl)pyridin-4-...) Show SMILES CC(=O)Nc1ccc(OC(=O)c2cccnc2Nc2ccnc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15F3N4O3/c1-12(28)26-13-4-6-15(7-5-13)30-19(29)16-3-2-9-25-18(16)27-14-8-10-24-17(11-14)20(21,22)23/h2-11H,1H3,(H,26,28)(H,24,25,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by liquid scintillation spectroscopy				J Med Chem 53: 2286-98 (2010) Article DOI: 10.1021/jm901891p BindingDB Entry DOI: 10.7270/Q2833S4K
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