Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1 [30-579]' and Ligand = 'BDBM50402695'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50402695 (CHEMBL2207356) Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-4-1-3-19(17-22)18-29-13-15-30(16-14-29)25(32)28-24-6-2-5-23-27-11-12-31(23)24/h1-12,17H,13-16,18H2,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development, LLC Curated by ChEMBL					Assay Description Inhibition of rat FAAH preincubated for 60 mins				Bioorg Med Chem Lett 22: 7357-62 (2012) Article DOI: 10.1016/j.bmcl.2012.10.076 BindingDB Entry DOI: 10.7270/Q28S4R30
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50402695 (CHEMBL2207356) Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3cccc4nccn34)c2)cc1 Show InChI InChI=1S/C25H24ClN5O2/c26-20-7-9-21(10-8-20)33-22-4-1-3-19(17-22)18-29-13-15-30(16-14-29)25(32)28-24-6-2-5-23-27-11-12-31(23)24/h1-12,17H,13-16,18H2,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Companies of Johnson& Johnson, L.L.C. Curated by ChEMBL					Assay Description Apparent inhibition of recombinant rat FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation anal...				Bioorg Med Chem Lett 26: 3109-14 (2016) Article DOI: 10.1016/j.bmcl.2016.05.001 BindingDB Entry DOI: 10.7270/Q25B04F3
					More data for this Ligand-Target Pair