Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM142344'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM142344 (US8933099, 106) Show SMILES CCOCCOc1cc2n(ccc2cc1Oc1ccnc(NC(=O)c2ccc(CN3CC[C@@H](O)C3)cc2)c1)C(=O)NC |r| Show InChI InChI=1S/C31H35N5O6/c1-3-40-14-15-41-27-18-26-23(9-13-36(26)31(39)32-2)16-28(27)42-25-8-11-33-29(17-25)34-30(38)22-6-4-21(5-7-22)19-35-12-10-24(37)20-35/h4-9,11,13,16-18,24,37H,3,10,12,14-15,19-20H2,1-2H3,(H,32,39)(H,33,34,38)/t24-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	25
Eisai R&D Management Co., Ltd. US Patent					Assay Description In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR1 protein is measured.To each well of a flat b...				US Patent US8933099 (2015) BindingDB Entry DOI: 10.7270/Q28S4NMG
					More data for this Ligand-Target Pair