Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM247354'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM247354 (US9447091, 190) Show SMILES COc1ccc(c(F)c1)-c1cc(NC(C)=O)cc(c1)-n1cnc2cc(ccc12)-c1cnn(C)c1 Show InChI InChI=1S/C26H22FN5O2/c1-16(33)30-20-8-18(23-6-5-22(34-3)12-24(23)27)9-21(11-20)32-15-28-25-10-17(4-7-26(25)32)19-13-29-31(2)14-19/h4-15H,1-3H3,(H,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
ORION CORPORATION US Patent					Assay Description Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...				US Patent US9447091 (2016) BindingDB Entry DOI: 10.7270/Q2TM792J
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