Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM445223'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR1 (FGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR1 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM445223 (US10669235, Example 14 | US10669235, Example 50 | ...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H36N4O5/c1-21-18-27-28(19-26(21)33(41)42-2)36-32(40)29(27)30(23-6-4-3-5-7-23)35-25-10-8-24(9-11-25)31(39)34-20-22-12-14-37(15-13-22)16-17-38/h3-11,18-19,22,35,38H,12-17,20H2,1-2H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	19.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR1 (FGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR1 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair