Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM4609'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM4609 (1,6-naphthyridine deriv. 11 | 1-[7-amino-3-(2,6-di...) Show SMILES CC(C)(C)NC(=O)Nc1nc2cc(N)ncc2cc1-c1c(Cl)cccc1Cl |(-.23,-6.63,;1.1,-5.86,;1.1,-7.4,;2.59,-6.26,;1.1,-4.32,;2.43,-3.55,;3.77,-4.32,;2.43,-2.01,;1.1,-1.24,;-.23,-2.01,;-1.57,-1.18,;-2.9,-1.95,;-4.23,-1.18,;-5.57,-1.95,;-4.23,.36,;-2.9,1.13,;-1.57,.36,;-.23,1.07,;1.1,.3,;2.43,1.07,;3.78,.32,;3.78,-1.22,;5.1,1.11,;5.08,2.65,;3.73,3.4,;2.41,2.61,;1.08,3.38,)| Show InChI InChI=1S/C19H19Cl2N5O/c1-19(2,3)26-18(27)25-17-11(16-12(20)5-4-6-13(16)21)7-10-9-23-15(22)8-14(10)24-17/h4-9H,1-3H3,(H2,22,23)(H2,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 43: 4200-11 (2000) Article DOI: 10.1021/jm000161d BindingDB Entry DOI: 10.7270/Q2JW8C3G
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