Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM4644'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM4644 (Anilinoquinazoline deriv. 27 | N-(4-Chloro-2-fluor...) Show SMILES COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCn1ccnc1 Show InChI InChI=1S/C20H17ClFN5O2/c1-28-18-9-14-17(10-19(18)29-7-6-27-5-4-23-12-27)24-11-25-20(14)26-16-3-2-13(21)8-15(16)22/h2-5,8-12H,6-7H2,1H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	25
AstraZeneca					Assay Description An ELISA assay was used to determine the ability of inhibitor to inhibit FGFR-1 TK activity. The compounds were incubated with enzyme 20 min at room ...				J Med Chem 42: 5369-89 (1999) Article DOI: 10.1021/jm990345w BindingDB Entry DOI: 10.7270/Q2F47MBM
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