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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50234572'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50234572
PNG
(CHEMBL4086643)
Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(F)c(c3)C#Cc3cncc4ccccc34)cc2C(F)(F)F)CC1
Show InChI InChI=1S/C31H26F4N4O/c1-38-12-14-39(15-13-38)20-25-8-10-26(17-28(25)31(33,34)35)37-30(40)22-9-11-29(32)21(16-22)6-7-24-19-36-18-23-4-2-3-5-27(23)24/h2-5,8-11,16-19H,12-15,20H2,1H3,(H,37,40)
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Similars

Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 after 60 mins by ELISA method


Eur J Med Chem 126: 122-132 (2017)


Article DOI: 10.1016/j.ejmech.2016.10.003
BindingDB Entry DOI: 10.7270/Q2FX7CQK
More data for this
Ligand-Target Pair