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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM50345454'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50345454
PNG
(CHEMBL1784726 | Ethyl 8-Oxo-3-(propylthio)-8H-acen...)
Show SMILES CCCSc1ccc2c3c(C(=O)OCC)c(=O)nc3c3cccc1c23
Show InChI InChI=1S/C20H17NO3S/c1-3-10-25-14-9-8-12-15-11(14)6-5-7-13(15)18-16(12)17(19(22)21-18)20(23)24-4-2/h5-9H,3-4,10H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of FGFR1 using poly(Glu-Tyr)4:1 as substrate after 60 mins by ELISA


J Med Chem 54: 3732-45 (2011)


Article DOI: 10.1021/jm200258t
BindingDB Entry DOI: 10.7270/Q29W0FTH
More data for this
Ligand-Target Pair