Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM6175'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM6175 (1,6-naphthyridine 41 | 1-(7-{[3-(benzyloxy)propyl]...) Show SMILES COc1cc(OC)cc(c1)-c1cc2cnc(NCCCOCc3ccccc3)cc2nc1NC(=O)NC(C)(C)C Show InChI InChI=1S/C31H37N5O4/c1-31(2,3)36-30(37)35-29-26(22-14-24(38-4)17-25(15-22)39-5)16-23-19-33-28(18-27(23)34-29)32-12-9-13-40-20-21-10-7-6-8-11-21/h6-8,10-11,14-19H,9,12-13,20H2,1-5H3,(H,32,33)(H2,34,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description Compounds were evaluated for their ability to prevent phosphorylation of a model glutamate-tyrosine copolymer substrate by isolated human FGFR-1, mou...				J Med Chem 48: 4628-53 (2005) Article DOI: 10.1021/jm0500931 BindingDB Entry DOI: 10.7270/Q2DV1H3W
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