Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1 [308-731]' and Ligand = 'BDBM350068'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 [308-731] (Homo sapiens (Human))	BDBM350068 (US10208024, Example 67 | US10766881, Example 67) Show SMILES COCCN1CCC(CC1)n1cc(cn1)-c1cnc(N)c(n1)-c1ccc(=O)n(n1)-c1cc(OC)cc(OC)c1C Show InChI InChI=1S/C28H34N8O4/c1-18-24(13-21(39-3)14-25(18)40-4)36-26(37)6-5-22(33-36)27-28(29)30-16-23(32-27)19-15-31-35(17-19)20-7-9-34(10-8-20)11-12-38-2/h5-6,13-17,20H,7-12H2,1-4H3,(H2,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Array Biopharma Inc. US Patent					Assay Description To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...				US Patent US10766881 (2020) BindingDB Entry DOI: 10.7270/Q2BZ693Q
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