Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM130896'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM130896 (US8829199, 190) Show SMILES Cc1nc2ccc(cc2n1)-n1ncc(C(=O)c2cc3c(cc(cc3[nH]2)C(C)(C)C)C(C)(C)C)c1N Show InChI InChI=1S/C28H32N6O/c1-15-31-21-9-8-17(12-23(21)32-15)34-26(29)19(14-30-34)25(35)24-13-18-20(28(5,6)7)10-16(27(2,3)4)11-22(18)33-24/h8-14,33H,29H2,1-7H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Seiyaku Kabushiki Kaisha; F. Hoffmann-La Roche AG US Patent					Assay Description The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...				US Patent US8829199 (2014) BindingDB Entry DOI: 10.7270/Q26T0KB8
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