Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM161397'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161397 (US10124003, Ex. Compound 10 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn(C2CN(C2)C(=O)C#CCO)c2ncnc(N)c12 Show InChI InChI=1S/C22H20N6O4/c1-31-16-8-14(9-17(10-16)32-2)5-6-18-20-21(23)24-13-25-22(20)28(26-18)15-11-27(12-15)19(30)4-3-7-29/h8-10,13,15,29H,7,11-12H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161397 (US10124003, Ex. Compound 10 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn(C2CN(C2)C(=O)C#CCO)c2ncnc(N)c12 Show InChI InChI=1S/C22H20N6O4/c1-31-16-8-14(9-17(10-16)32-2)5-6-18-20-21(23)24-13-25-22(20)28(26-18)15-11-27(12-15)19(30)4-3-7-29/h8-10,13,15,29H,7,11-12H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021) BindingDB Entry DOI: 10.7270/Q2319ZZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161397 (US10124003, Ex. Compound 10 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn(C2CN(C2)C(=O)C#CCO)c2ncnc(N)c12 Show InChI InChI=1S/C22H20N6O4/c1-31-16-8-14(9-17(10-16)32-2)5-6-18-20-21(23)24-13-25-22(20)28(26-18)15-11-27(12-15)19(30)4-3-7-29/h8-10,13,15,29H,7,11-12H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020) BindingDB Entry DOI: 10.7270/Q23N26F5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161397 (US10124003, Ex. Compound 10 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn(C2CN(C2)C(=O)C#CCO)c2ncnc(N)c12 Show InChI InChI=1S/C22H20N6O4/c1-31-16-8-14(9-17(10-16)32-2)5-6-18-20-21(23)24-13-25-22(20)28(26-18)15-11-27(12-15)19(30)4-3-7-29/h8-10,13,15,29H,7,11-12H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair