Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM161436'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161436 (US9108973, 49) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN2CC[C@H](F)C2)c2ncnc(N)c12 |r| Show InChI InChI=1S/C28H31FN6O3/c1-37-23-12-19(13-24(14-23)38-2)5-6-20-15-35(28-26(20)27(30)31-18-32-28)22-8-11-34(17-22)25(36)4-3-9-33-10-7-21(29)16-33/h3-4,12-15,18,21-22H,7-11,16-17H2,1-2H3,(H2,30,31,32)/b4-3+/t21-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
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